Rheology, granule growth and granule strength: Application to the wet granulation of lactose–MCC mixtures
نویسندگان
چکیده
منابع مشابه
Evaluation of the effect of granulation processing parameters on the granule properties: Lactose- Cornstarch case study
Understanding the relationship between processing parameters of fluidized bed wet granulation and the characteristics of intermediate and final products is crucial in the pharmaceutical processes. This research examined a fluidized bed wet granulation process containing a cornstarch solution as binder and lactose particles as powder. The design of experiment (DoE) was performed according to an ...
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Granule Strength Determination and Compactibility of Granules of Varying Density
Purpose: As in-line process analytics are becoming more widely accepted, it is important to illustrate that a measurement of interest will provide the expected outcome if that control point has reached a desired level. This methodology is especially true for novel applications. The purpose of this work was to investigate the role of densification during high shear granulation and the resulting ...
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ژورنال
عنوان ژورنال: Powder Technology
سال: 2011
ISSN: 0032-5910
DOI: 10.1016/j.powtec.2010.08.041